| Sep. 1 | Southern California | 27 | LSU | 20 | ABC | 7:30 PM |
| Sep. 7 | Nicholls St. | 21 | LSU | 44 | ESPN+ | 7:30 PM |
| Sep. 14 | LSU | 36 | South Carolina | 33 | ABC | Noon |
| Sep. 21 | UCLA | 17 | LSU | 34 | TBA | TBA |
| Sep. 28 | South Alabama | 10 | LSU | 42 | SECN | 7:45 PM |
| Oct. 12 | Ole Miss | 26 | LSU | 29 | ABC | 4:30 PM |
| Oct. 19 | LSU | 34 | Arkansas | 10 | ESPN | 4:00 PM |
| Oct. 26 | LSU | 23 | Texas A&M | 38 | ESPN | 7:30 |
| Nov. 9 | Alabama | 42 | LSU | 13 | ABC | 7:30 PM |
| Nov. 16 | LSU | 16 | Florida | 27 | ABC | 3:30 PM |
| Nov. 23 | Vanderbilt | 17 | LSU | 24 | SEC | 7:45 PM |
| Nov. 30 | Oklahoma | 17 | LSU | 37 | ESPN | 7:00 PM |
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